Case 2: Premolar extraction of immediate and delayed implants and autogenous graft

Case study photographs courtesy of Dr. Yuval Zubery, Ramat Hasharon, Israel.

Patient Presentation

A 58-year-old male presented with a vertical root fracture in tooth #5, accompanied by a buccal abscess and a missing tooth #4. Following extraction, loss of buccal and palatal bone was extensive.

Delayed implant #4 and immediate implant #5 were placed and the defect was filled with autogenous bone chips. OSSIX Plus resorbable collagen membrane was placed over the defect, and the site was closed with a coronally positioned tension-free flap using 6-0 nylon sutures.

Re-entry at second-stage implant surgery (5.5 months later) revealed complete bone regeneration around the mesial implant. Post-op radiographs revealed complete resolution of the defect around the implant.

To order any OSSIX product, call OraPharma at 866-273-7846


OSSIX® Bone is a sterile, biocompatible bone grafting material aimed to fill, augment, or reconstruct periodontal and bony defects of the maxillo-facial complex.


  • OSSIX® Bone must not be used in:
    • Patients with known collagen hypersensitivity.
    • Patients with a sensitivity to porcine-derived materials.
    • Patients suffering from autoimmune diseases and connective tissue diseases, such as: systemic lupus erythematosus, dermatomyositis, etc.
    • Patients with acute or chronic infection (osteomyelitis) at the surgical site.
    • Patients with vascular impairment at the implant site.
    • Patients with uncontrolled periodontal disease.
    • Patients that have received or are currently receiving treatment with bisphosphonates.
    • OSSIX® Bone should not be used in the presence of infected wounds at the site of implantation.
  • OSSIX® Bone is intended for a single use only. Do not re-sterilize or reuse.
  • As OSSIX® Bone contains collagen, allergic reactions (e.g. erythema, swelling, induration and/or pruritus at treatment site) may not be entirely excluded.

Please see accompanying Instructions for Use or Click here for Instructions for Use.